Blood Transfusion Reactions
| ||
Type
|
Cause
|
Manifestation
|
Allergic
|
Sensitivity to foreign
proteins.
|
■ Hives,
urticaria, flushing
■ Fever
|
Febrile, nonhemolytic
|
Sensitization to
donor’s WBC,
platelets, and/or
plasma proteins.
|
■ Fever,
chills, and flushing
■ HA
and muscle aches
■ Respiratory
distress
■ Cardiac dysrhythmias
|
Acute
hemolytic
|
ABO incompatibility
reaction to RBC
antigens.
|
■ Fever,
chills, and flushing
■ Low
back pain
■ Tachycardia
and hypotension
■ Vascular
collapse
■ Cardiac arrest
|
Anaphylactic
|
Administration of
donor IgA proteins
to recipient with
anti-IgA antibodies.
|
■ Urticaria
■ Restlessness
■ Wheezing
■ Shock
and cardiac arrest
|
Circulatory
overload
|
Infusion of blood at a
rapid rate that leads
to fluid volume
excess.
|
■ Pulmonary
congestion
■ Restlessness
■ Cough,
shortness of breath
■ HTN
■ Distended neck veins
|
Bacteremia
|
Infusion of blood
infected with
bacteria.
|
■ Fever
and chills
■ Vomiting
and diarrhea
■ Hypotension
■ Septic shock
|
1/10/14
Blood Transfusion Reactions
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