10/28/15

discharge

The discharge - A visible emission of fluid from an orifice or a break in the skin (such as a wound or burst boil).

A discharge may be a normal occurrence, as in some types of vaginal discharge, but it could also be due to an infection or to inflammation, as occurs, for example, in rhinitis (inflammation of the lining of the nasal passages), urethritis (infection of the urethra), or in proctitis (infection of the rectum).
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discectomy

The discectomy - A procedure in which part or all of a damaged intervertebral disc (see disc, intervertebral) is surgically removed.

Discectomy relieves the symptoms of disc prolapse (in which an intervertebral disc ruptures and part of its pulpy core protrudes) by relieving the pressure that the protruding tissue places on nerves or nerve roots.
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disaccharide

The disaccharide - A carbohydrate comprising two linked monosaccharide units. Lactose, maltose, and sucrose are all disaccharides.
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disability

The disability - A loss or impairment of normal functioning or activity as the result of a physical or mental impediment. (See also handicap; rehabilitation.)
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dipyridamole

The dipyridamole - A drug that reduces the stickiness of platelets in the blood and thereby helps to prevent the formation of abnormal blood clots within arteries.

Dipyridamole may be used with aspirin or warfarin to prevent the formation of blood clots following stroke or transient ischaemic attack or in people who have artificial heart valves. Possible adverse effects may include headache, flushing, and dizziness.
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dipsomania

The dipsomania - A form of alcohol dependence in which periods of excessive drinking and craving for drink alternate with periods of relative sobriety.
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diphtheria

The diphtheria - A bacterial infection that causes a sore throat, fever, and sometimes serious or even fatal complications. Diphtheria is caused by the bacillus CORYNEBACTERIUM DIPHTHERIAE.

The disease is now rare in developed countries as a result of mass immunization. In the UK, the vaccine is given at 2, 3, and 4 months, 3–5 years, and 13–18 years of age.

SYMPTOMS
The infection may begin in the throat or in the skin. In the throat, multiplication of bacteria causes the formation of a membrane that may cover the tonsils and spread up over the palate or down to the larynx (voicebox) and the trachea (windpipe), causing breathing difficulty and a husky voice. Other symptoms
include enlarged lymph nodes in the neck, an increased heart rate, and mild fever. If infection is confined to the skin, the bacteria may produce a yellowish lesion covered by a hard membrane.

Life-threatening symptoms occur only in people who are not immune to the disease.They are caused by a toxin that is released by the bacteria and affects the heart and nervous system. Occasionally, a victim collapses and dies within a day of developing throat symptoms. More often, the victim is recovering from diphtheria when heart failure or paralysis of the throat or limbs develops. These complications can occur up to seven weeks after the onset of infection in the throat.

TREATMENT
Diphtheria is treated with antibiotics; in addition, an antitoxin is given to neutralize the bacterial toxin. If severe breathing difficulties develop, a tracheostomy (the surgical introduction of a breathing tube into the windpipe) may also be necessary.
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diphenoxylate

The diphenoxylate - An antidiarrhoeal drug that is chemically related to the opioid analgesic drugs (painkillers). Diphenoxylate lessens the contractions of the muscles in the walls of the intestines, thereby reducing the frequency of bowel movements.
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diphenhydramine

The diphenhydramine - An antihistamine drug that is used to treat allergic disorders such as urticaria (nettle rash) and allergic rhinitis (hay fever).

Diphenhydramine is also used for the relief of temporary sleep disturbance, and is an ingredient in some cough remedies. It can cause drowsiness, dry mouth, and blurred vision.
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dioxin

The dioxin - The name of a highly toxic group of chemicals. Dioxins are contaminants of some defoliant weedkillers (see defoliant poisoning; Agent Orange).
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dioptre

The dioptre - A unit of the power of refraction (the “strength”) of a lens; the greater the power, the stronger the lens.

Lenses that cause parallel light rays to converge have a positive dioptric number and are used to correct longsightedness (see hypermetropia). Those that cause light rays to diverge have a negative number and are used to correct shortsightedness (see myopia).
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diltiazem

The diltiazem - dimeticone A silicone-based substance, also known as simeticone, that is used in barrier creams and as an antifoaming agent in antacid preparations.
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diltiazem

The diltiazem - A calcium channel blocker drug that is used in the treatment of hypertension (high blood pressure) and angina pectoris (chest pain due to impaired blood supply to the heart muscle).

Side effects of diltiazem may include headaches, loss of appetite, nausea, constipation, and swollen ankles.
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dilator

The dilator - An instrument used for stretching and enlarging a narrowed body cavity, passage, or opening, for example to enable an investigative procedure or surgery.
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dilatation

The dilatation - A condition in which a body cavity, passage, or opening is enlarged or stretched due to normal physiological processes (such as childbirth) or because of the effects of disease.

The term “dilatation” also refers to medical procedures for achieving such enlargement, as in dilatation and curettage b (see D and C).
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dihydrocodeine

The dihydrocodeine - A type of opioid analgesic drug (painkiller). Side effects of dihydrocodeine include nausea and vomiting.
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Di Guglielmo’s disease

The Di Guglielmo’s disease - A form of acute myeloblastic leukaemia (see leukaemia, acute) characterized by excessive numbers of red blood cells in the bone marrow and bloodstream.
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digoxin

The digoxin - The most widely used of the digitalis drugs. Digoxin is used in the treatment of heart failure and certain types of arrhythmia (irregular heartbeat), such as atrial fibrillation.

Blood tests are sometimes needed to ensure the correct digoxin dose, especially in patients with kidney disease. An excessive dose may cause headache, loss of appetite, nausea and vomiting, and visual disturbances. Digoxin occasionally disrupts the normal heartbeat, causing heart block.
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digitoxin

The digitoxin - A long-acting digitalis drug that is used to treat heart failure and certain types of arrhythmia (irregular heartbeat).
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digitalis drugs

The digitalis drugs - A group of drugs that are extracted from plants belonging to the foxglove family. They are used to treat heart conditions, most commonly atrial fibrillation (irregular, rapid beating of the upper chambers of the heart). Those most frequently used are digitoxin and digoxin.
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digestive system

The digestive system - The group of organs responsible for digestion. The digestive system consists of the digestive tract (also known as the alimentary tract or canal) and various associated organs.

STRUCTURE
The mouth, pharynx (throat), oesophagus (gullet), stomach, intestines, and anus make up the digestive tract. The intestines consist of the small intestine (comprising the duodenum, jejunum, and ileum) and the large intestine (comprising the caecum, colon, and rectum).

Associated organs, such as the salivary glands, the liver, and pancreas, secrete digestive juices that help break down food as it goes through the tract.

FUNCTION
Food and the products of digestion are moved from the throat to the rectum by peristalsis (waves of muscular contractions of the intestinal wall). Food is broken down into simpler substances before being absorbed into the bloodstream. Physical breakdown is performed by the teeth, which cut and chew, and the stomach, which churns the food. Chemical breakdown of food is performed by the action of enzymes (biological catalysts), acids, and salts.

Carbohydrates are broken down into simple sugars. Proteins are broken down into polypeptides, peptides, and amino acids. Fats are broken down into glycerol, glycerides, and fatty acids.

In the mouth, saliva lubricates food and contains enzymes that begin to break down carbohydrates. The tongue moulds food into balls (called boli) for easy swallowing. The food then passes into the pharynx, from where it is pushed into the oesophagus and is then squeezed down into the stomach. Once in the stomach, the food is mixed with hydrochloric acid and pepsin.

These substances, produced by the stomach lining, help to break down proteins. When the food has been converted to a semi-liquid consistency, it passes into the duodenum, where bile salts and acids (produced by the liver) help to break down the fats it contains. Digestive juices released by the pancreas into the duodenum contain enzymes that further break down food.

Breakdown concludes in the small intestine, carried out by enzymes that are produced by glands in the intestinal lining. Nutrients are absorbed in the small intestine through tiny projections from the intestinal wall, called villi.

The food residue enters the large intestine, where much of the water it contains is absorbed by the lining of the colon. Undigested matter is expelled via the rectum and anus as faeces.
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digestion

The digestion - The process by which food is broken down into smaller components that can be transported and used by the body. (See also digestive system).
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Digestive Process

Digestive Process
The Digestive Process - Digestion starts when food enters the mouth. It continues as the food is propelled through the digestive tract by waves of muscular contractions (peristalsis).

The digestive process also involves various organs (the salivary glands, liver, gallbladder, and pancreas), which produce enzymes and acids that help to break down the food.
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DiGeorge syndrome

The DiGeorge syndrome - An immunodeficiency disorder that results in a failure of the immune system’s cells to fight infection. The disorder is hereditary and congenital (present at birth). In DiGeorge syndrome, the thymus gland is absent or fails to develop normally.

The thymus is a key part of the immune system, so its absence may allow persistent, serious infections to develop. Children with DiGeorge syndrome are susceptible to opportunistic infections, such as candidiasis (thrush), and there may be evidence of failure to thrive (restricted growth). In addition, heart abnormalities and hypocalcaemia (abnormally low levels of calcium in the blood) may occur.

Transplants of thymus tissue, or bone marrow transplants, may be successful in treating the immunodeficiency.

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diflunisal

The diflunisal - A nonsteroidal anti-inflammatory drug (NSAID) used to relieve joint pain and stiffness in types of arthritis. The drug is also given for back pain, sprains, and strains. Side effects include nausea, diarrhoea, and a rash.
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diffusion

The diffusion - The spread of a substance (by movement of its molecules) in a fluid from an area of high concentration to one of lower concentration, thus producing a uniform concentration throughout.
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differentiation

The differentiation - The process by which the cells of the early embryo, which are almost identical and have not yet taken on any particular function, gradually diversify to form the distinct tissues and organs of the more developed embryo.

The word “differentiation” is also used in the assessment of cancer; it means the degree to which the microscopic appearance of cancerous tissue resembles normal tissue.
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differential diagnosis

The differential diagnosis - One of two or more different disorders that could be the cause of a patient’s symptoms. If certain symptoms, such as abdominal pain, might be caused by various disorders, a doctor will carry out further tests, observe the patient’s response to particular treatments, or monitor the course of the disease in order to arrive at the true diagnosis.
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diethylstilbestrol

The diethylstilbestrol - A synthetic form of the female sex hormone oestrogen, occasionally used to treat prostate cancer (see prostate, cancer of) and, in postmenopausal women only, to treat breast cancer. Common adverse effects include nausea, oedema (fluid retention) and breast enlargement (gynaecomastia) in men.
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dietetics

The dietetics - The application of nutritional science to maintain or restore health. Dietetics involves not only a knowledge of the composition of foods, the effects of cooking and processing various foods, and dietary requirements, but also ofpsychological aspects of diet, such as eating habits (see nutrition).
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dietary amenorrhoea

The dietary amenorrhoea - A form of amenorrhoea (cessation of menstruation) caused by major weight loss, although not necessarily by a lack of food. In some cases, the weight loss is deliberate and severe (see anorexia nervosa). Absence of menstrual periods occurs because the loss of body fat disrupts the levels of the female sex hormone oestrogen.
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diet and disease

The diet and disease - A variety of diseases are linked with diet. Diseases due to a deficiency of nutrients are a major problem in poor countries. In children, starvation or malnutrition may result in marasmus or kwashiorkor, while vitamin deficiencies may cause rickets or keratomalacia (a condition that causes blindness). Vitamin deficiencies may lead to beriberi, pellagra, or scurvy. In affluent countries, diseases due to deficiency are rare, occurring only in certain groups of people (such as alcoholics).

Instead, many disorders are due at least partly to overconsumption of food. Overeating causes weight gain and, in severe cases, obesity. The latter condition places a person at increased risk of disorders such as diabetes mellitus, stroke, coronary artery disease, and osteoarthritis. Diets causing weight gain tend to be high in fats and sugar, but may be low in valuable components such as fibre and vitamins.

GOOD DIETARY HABITS
• Eat fresh rather than preserved, packaged, or convenience foods.
• Eat plenty of vegetables and at least five portions of fruit every day. When raw or lightly cooked, they retain a higher nutritional value.
• Eat whole-grain products, including wholemeal bread.
• Cut down consumption of red meat; instead, eat fish, poultry, and pulses.
• Keep the fat content of your diet low and use polyunsaturated fats and vegetable oils rather than saturated fats.
• Cut down on sugar and salt in all foods.
• When choosing filling foods, eat potatoes in their skins, pasta, or rice.



FATS
A diet that is high in fats, particularly saturated fats (see fats and oils), may contribute to atherosclerosis (narrowing of the arteries due to accumulation of fatty deposits on the arterial walls); this, in turn, may lead to cardiovascular diseases such as coronary artery disease, stroke, and peripheral vascular disease. A high-fat diet has also been linked with cancer of the bowel (see colon, cancer of) and breast cancer.

ALCOHOL
Overconsumption of alcohol can lead to alcohol-related disorders. In the digestive system, it may cause cirrhosis of the liver, pancreatitis, and oesophageal cancer
(see oesophagus, cancer of); in addition, people who are dependent on alcohol often become malnourished. Drinking too much alcohol may cause cardiovascular problems such as hypertension (high blood pressure) and heart failure; neurological disorders such as Wernicke– Korsakoff syndrome; and mental or behavioural problems such as depression or violence.

SALT
A high salt intake may predispose a person to hypertension.

FIBRE
Fibre, found in fruit, vegetables, and grains, provides bulk, which helps the passage of food through the intestine and also aids the absorption of nutrients (see fibre, dietary). A lack of fibre is thought to be a contributory factor in digestive disorders such as diverticular disease (a condition in which abnormal pouches form in the colon), chronic constipation, and haemorrhoids.

VITAMINS
Many people’s diets contain too few natural vitamins; to remedy this problem, it is better to eat vitamin-rich foods than to take vitamin supplements. Women who are planning a pregnancy need to increase their intake of folic acid in order to reduce the risk of neural tube defects in the baby.

FOOD ALLERGIES
Many illnesses are commonly ascribed to food allergy, but it is only rarely that a definite link is proved. Nut allergies, which may cause the life-threatening reaction anaphylaxis, and coeliac disease (a reaction to the protein gluten, which is found in wheat and other cereals) are examples of genuine food allergies. (See also nutritional disorders.)
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Didronel

The Didronel - A brand name for disodium etidronate (see etidronate, disodium), which is a bisphosphonate drug. Didronel is used to treat bone disorders such as Paget’s disease and osteoporosis.
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diclofenac

The diclofenac - A nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain and stiffness in arthritis and to hasten recovery following injury to muscles or ligaments. Possible adverse effects of the drug include nausea, abdominal pain, and peptic ulcer.
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diazepam

The diazepam - One of the benzodiazepine drugs, used mainly for the short-term treatment of anxiety and insomnia.

Diazepam is also prescribed as a muscle-relaxant drug, as an anticonvulsant drug in the emergency treatment of epilepsy, and to treat alcohol withdrawal symptoms in people who are dependent on alcohol. It may also be administered intravenously in order to produce sedation in people undergoing certain medical procedures, such as endoscopy.

Diazepam may cause drowsiness, dizziness, and confusion; therefore, driving and hazardous work should be avoided while taking the drug. Alcohol increases the sedative effects of the drug, and should not be consumed while diazepam is being used.

Like other benzodiazepines, diazepam can be habit-forming if it is taken regularly, and its effects diminish with prolonged use. Individuals who have been taking diazepam regularly for more than two weeks should never stop their treatment suddenly; instead, they should gradually decrease the dose of the drug, under medical supervision, in order to avoid withdrawal symptoms (such as anxiety, sweating, or, rarely, after large doses, seizures).
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diathesis

The diathesis - A predisposition towards certain disorders. For example, a bleeding diathesis is present when a bleeding disorder (such as haemophilia) makes a person susceptible to prolonged bleeding after an injury. A diathesis may be inherited or it may be acquired as a result of an illness or an injury.
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diathermy

The diathermy - The production of heat in a part of the body using high-frequency electric currents or microwaves. Diathermy can be used to increase blood flow and to reduce some types of deep-seated pain, for example in rheumatic or arthritic conditions.

Diathermy can also be used to destroy tumours and diseased areas of tissue without causing bleeding. A diathermy knife is used by surgeons to coagulate bleeding vessels or to separate tissues without causing them to bleed (see electrocoagulation).
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diastolic pressure

The diastolic pressure - The lowest level of blood pressure measured in the main arteries. Diastolic pressure is the pressure between heartbeats, when the ventricles (the lower chambers of the heart) are relaxed and filling with blood. Systolic pressure, the highest level of blood pressure in the main arteries, occurs when the ventricles of the heart contract.

The normal range of blood pressure varies with age and between individuals, but a young adult usually has a diastolic pressure of about 80 mmHg (mm of mercury) and a systolic pressure of about 120 mmHg. A persistently high diastolic pressure occurs in most cases of hypertension.
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diastole

The diastole - The period in the heartbeat cycle when the heart muscle is at rest; it alternates with systole, the period of muscular contraction. (See also cardiac cycle).

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diarrhoea

The Diarrhoea - An increase in the fluidity, frequency, or volume of bowel movements, as compared to the usual pattern for a particular individual. Diarrhoea may be acute or chronic. The condition can be very serious in infants and in elderly people because of the risk of severe, potentially fatal, dehydration.

CAUSES:
Acute diarrhoea is usually a result of consuming food or water contaminated with certain bacteria or viruses (see food poisoning). Infective gastroenteritis also causes diarrhoea and may be acquired as a result of droplet infection. Other causes of acute diarrhoea include anxiety and, less commonly, amoebiasis, shigellosis, typhoid fever and paratyphoid fever, drug toxicity, food allergy, and food intolerance.

Chronic diarrhoea generally takes the form of repeated attacks of acute diarrhoea. Such a pattern may be the result of an intestinal disorder such as Crohn’s disease, ulcerative colitis, cancer of the colon (see colon, cancer of), or irritable bowel syndrome. Diarrhoea that recurs, persists for more than a week, or is accompanied by blood requires medical investigation.

TREATMENT:
The water and electrolytes (salts) lost during a severe attack of diarrhoea need to be replaced to prevent dehydration. Ready-prepared powders of electrolyte mixtures can be bought from chemists (see rehydration therapy). Antidiarrhoeal drugs, such as diphenoxylate and loperamide may help if the diarrhoea is disabling. They should not, however, be used to treat attacks of diarrhoea in children.

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diaphysis

The diaphysis - The shaft, or central portion, of a long bone, such as the femur (thigh-bone). During bone formation, the epiphysis (end of the long bone) develops independently from the diaphysis, as they are initially separated by a mass of cartilage known as the epiphyseal plate. The diaphysis and epiphysis eventually fuse to form a complete bone.
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anatomy of the diaphragm

anatomy of the diaphragm
The anatomy of the diaphragm - The diaphragm is attached to the spine, the lower pairs of ribs, and the lower end of the sternum (breastbone). Its muscle fibres converge on the central tendon, which is a thick, flat plate of dense fibres.

There are openings in the diaphragm for the oesophagus, the phrenic nerve (which controls diaphragm movements and hence breathing), and the aorta and vena cava (the body’s main blood vessels).
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diaphragm muscle

The diaphragm muscle - The dome-shaped sheet of muscle that separates the chest from the abdomen. The diaphragm is attached to the spine, ribs, and sternum (breastbone). It has openings for the oesophagus and major nerves and blood vessels.

The diaphragm plays an important role in breathing. During inhalation, its muscle fibres contract, causing it to move downwards and drawing air into the lungs. During exhalation, the diaphragm muscle relaxes and it moves upwards, causing air to leave the lungs. (See also breathing.)
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diaphragm, contraceptive

The diaphragm, contraceptive - A female barrier method of contraception in the form of a hemispherical dome of thin rubber with a metal spring in the rim.

The diaphragm is inserted into the vagina and positioned over the cervix. (See also contraception, barrier methods.)
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diaphragmatic hernia

The diaphragmatic hernia - The protrusion of an abdominal structure through the diaphragm muscle into the thorax (chest cavity).

The most common form of this problem is a hiatus hernia, in which part of the stomach protrudes through the space in the diaphragm that is normally occupied by the oesophagus.
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Dianette

The Dianette - A brand name for a combination of cyproterone acetate with ethinylestradiol (synthetic sex hormones). Dianette may be used to treat severe acne or hirsutism (excessive hairiness) in women.
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diamorphine

The diamorphine - A synthetic, opioid analgesic similar to morphine; diamorphine is another name for heroin. It is used to relieve severe pain and to relieve distress in acute heart failure.

Diamorphine carries the risk of dependence. It may cause nausea, vomiting, and constipation. (See also heroin abuse.)
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dialysis

The dialysis - A filtering technique used to remove waste products from the blood and excess fluid from the body as a treatment for kidney failure.

WHY IT IS DONE:
Each day, the kidneys normally filter about 1,500 litres of blood. They help to maintain the fluid and electrolyte balance of the body. Important minerals and nutrients, such as potassium, sodium, calcium, amino acids, glucose, and water are reabsorbed into the blood. Urea, excess minerals, toxins, and drugs are excreted in the urine.

Dialysis is used to perform this function in people whose kidneys have been damaged due to acute or chronic kidney failure.Without dialysis, wastes accumulate in the blood and the electrolyte levels become unbalanced; this may be life-threatening. In chronic kidney failure, patients may need to have dialysis several times a week for the rest of their lives or until they can be given a kidney transplant. In acute kidney failure, dialysis is carried out more intensively until the kidneys are working normally.

HOW IT IS DONE:
There are two methods: haemodialysis and peritoneal dialysis. In both procedures, excess water and wastes in the blood pass across a membrane into a solution called a dialysate, which is then discarded.

Haemodialysis filters out wastes by passing blood through an artificial kidney machine. The process needs to be performed three or four times a week, and each session lasts two to six hours. In peritoneal dialysis, the abdominal cavity is filled with dialysate, which is changed regularly, and the peritoneum (the membrane lining the abdominal cavity) acts as a natural filter. The procedure is often carried out overnight or continuously during the day and night.

RISKS

Both types of dialysis carry the risk of upsetting body chemistry and fluid balance, which can cause complications. In addition, peritoneal dialysis carries a risk of infection in the peritoneum.
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diagnostic ultrasound

The diagnostic ultrasound - The use of high-frequency sound waves to form images of internal organs and so help doctors to make diagnoses (see ultrasound scanning).

Certain forms of ultrasound scanning are used to form moving images, such as images of the flow of blood through the heart (see Doppler echocardiography).
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diagnosis

The diagnosis - The process of identifying or finding out the nature of a disorder. The doctor listens to a patient’s account of his or her illness, and may carry out a physical examination.

If further information is needed, tests or imaging procedures may be ordered after a provisional diagnosis has been formed (see Steps in diagnosing a condition box, previous page).
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How peritoneal dialysis is done

peritoneal dialysis

1. A small abdominal incision is made, and a catheter is inserted into the peritoneal cavity. A bag of dialysate is attached to the catheter; the fluid passes into the cavity, where it is left for several hours. Used fluid is then drained out of the abdomen.
peritoneal dialysis

2. Waste products, and excess water from the blood vessels lining the peritoneal cavity, seep through the peritoneal membrane into the cavity and mix with the dialysate. The fluid is allowed to drain out (by the release of a clamp) through the catheter and into the empty dialysate bag.

3. The bag is discarded and replaced with a bag containing fresh dialysate. The procedure, which takes about an hour, can be performed during the day or overnight.
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Diseased kidney

Diseased kidney
The Diseased kidney - The kidney at left was removed from a person with adult polycystic kidney disease – one of many disorders that may damage kidney function to the extent that dialysis is needed.

In people with damaged kidneys, the process of maintaining the balance of electrolytes and water, and
of excreting waste products, may fail, causing harmful, even life-threatening, effects. Dialysis can take
over the function of the kidneys until they start working normally again. Or dialysis can function for the kidneys for the rest of a seriously affected person’s life if a kidney transplant is not performed.
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Procedure for dialysis

The Procedure for dialysis - There are two methods of removing wastes from the blood and excess fluid from the body when the kidneys have failed. The first, haemodialysis, may also be used as emergency treatment in some cases of poisoning or drug overdose. It makes use of an artificial kidney (or “kidney machine”) and can be carried out at home. Peritoneal dialysis needs an abdominal incision, which is performed in hospital but may also be done at home.


HOW HAEMODIALYSIS IS DONE
1. Access to the bloodstream for dialysis is obtained by a shunt (in the short term or in an emergency) or an arteriovenous fistula, in which an artery is joined surgically to a vein.

2. A needle inserted into the shunt or fistula carries blood to the machine. The machine pumps the blood through a filter attached to its side. Once inside the filter, the blood flows on one side of a membrane,
and dialysate fluid flows on the other. Waste products and water pass from the blood, across the membrane, and into the dialysate fluid. The filtered blood returns from the machine to the body via
another needle inserted into the shunt or fistula.

3. The membrane separates the patient’s blood from a special fluid called dialysate. Wastes, toxic molecules, and excess fluid pass across the membrane from the blood into the dialysate.

4. The dialysate is discarded and the purified blood returned to the patient. Each session lasts from two to six hours.


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