Types
of Insulin
|
||||
Agent
|
Onset
|
Peak
|
Duration
|
|
Rapid-acting
insulins
|
insulin lispro (Humalog)
|
5 min
|
60–90 min
|
4–6 hours
|
insulin aspart (NovoLog)
|
10–20 min
|
1–3 hours
|
3–5 hours
|
|
Short-acting
insulins
|
concentrated insulin: Iletin II
regular (concentrated) Insulin U-500.
Caution: Do not administer
IV because of the potential for overdosage.
|
30–60 min
|
2–3 hour
|
5–7 hours
|
regular insulin: (Humulin R,
Insulin-Toronto, Novolin R, Iletin II Regular,
Velosulin BR)
Caution: Regular insulin is the only insulin that can be administered IV.
|
SC route:
30–60 min
IV route:
10–30 min
|
SC route:
2–4 hours
IV route:
15–30 min
|
SC route:
5–7 hours
IV route:
30–60 min
|
|
Intermediateacting
insulins
|
isophane (NPH): (Humulin N,
NPH
Iletin II, Novolin Ge NPH, Novolin N)
|
1–2 hours
|
8–12 hours
|
18–24 hours
|
lente: (Humulin L, Novolin Ge
Lente, Novolin L)
No longer manufactured as of July, 2005
|
1–2 hours
|
8–12 hours
|
18–24 hours
|
|
Long-acting
insulins
|
insulin glargine (Lantus)
Caution: Lantus insulin cannot be mixed
with other insulins; may cause
unpredictable results.
|
Onset: 1 hour. Provides a constant
concentration over a 24-hour period
with no pronounced peak.
|
Onset: 1 hour. Provides a constant
concentration over a 24-hour period
with no pronounced peak.
|
Onset: 1 hour. Provides a constant
concentration over a 24-hour period
with no pronounced peak.
|
insulin detemir (Levemir
|
2–4 hours
|
None
|
24 hours
|
|
ultralente: (Humulin U,
Novolin U)
No longer manufactured
|
4–8 hours
|
16–18 hours
|
36 hours
|
|
Pre-mixed
insulins
(Note: other
mixes are
available)
|
NPH/regular: (Humulin
50/50, Humulin
70/30, Novolin 70/30)
|
30–60 min
|
2–8 hours
|
24 hours
|
aspart protamine/aspart (NovoLog
Mix
70/30)
|
10–20 mi
|
2 1/2 hours
|
24 hours
|
|
lispro protamine/lispro (Humalog
Mix
75/25)
|
5 min
|
2 hours
|
22 hours
|
1/10/14
Types of Insulin
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